M Sakkal, AS Jarab, AZ Al Meslamani
First-author work on spatially resolved airway niches in asthma, mapping epithelial-immune microenvironments that shape disease heterogeneity.
Expert Review of Respiratory Medicine 20 (3), 307-320, 2026
A Abou Hajal, M Sakkal
We use AutoGluon to predict drug-drug interactions and show that automated model search with molecular fingerprints can match handcrafted pipelines while staying simple to reproduce.
Toxicology Mechanisms and Methods, 1-11, 2026
R Ghemrawi, M Sakkal, K Kayed, W Mousa, M Khair
Cross-sectional survey of public perceptions of AI-assisted cancer care in Abu Dhabi. Reports attitudes, trust gaps, and the demographic patterns that shape adoption.
Supportive Care in Cancer 34 (2), 162, 2026
M Sakkal, A Abou Hajal
A methodological audit of tumour-progression ML papers, showing how weak validation choices inflate apparent performance and what an honest benchmark would look like in oncology.
Computers in Biology and Medicine 191, 110156, 2025
M Sakkal, RWA Abdelmoteleb, A Al Ali, YAB Jardan, R Löbenberg, ...
First-author review of inhalable nanoparticle-based drug delivery for non-small cell lung cancer. Maps the design choices that improve targeting and the translational gaps still in the way.
Saudi Pharmaceutical Journal 33 (6), 50, 2025
N Al-Damook, M Sakkal, M Khair, WK Mousa, G Khoder, R Ghemrawi
Review of thymoquinone as a targeted cancer therapy. Walks through molecular mechanisms and the clinical prospects that depend on solving the formulation problem.
International Journal of Molecular Sciences 26 (22), 11029, 2025
M Sakkal, A Abou Hajal
First-author review of large language models in drug delivery. Covers what LLM-powered tools currently do for formulation and what would have to be true before they replace manual triage.
Journal of Pharmaceutical Sciences, 104147, 2025
N Atatreh, RE Mahgoub, R Ghemrawi, M Sakkal, N Sammani, M Khair, ...
Discovery of small ERK5 inhibitors through structure-based virtual screening, biological evaluation, and MD simulations. Reports candidates that survived in-vitro validation.
Molecules 30 (21), 4181, 2025
N Al-Damook, M Sakkal, S Kremesh, WK Mousa, M Khair, G Khoder, ...
Synergistic modulation of ER stress combined with insulin potentiation therapy for enhanced cancer treatment. Reports a combination strategy validated across cancer cell lines.
Cell Therapy & Engineering Connect 1 (1), 1-10, 2025
M Arafat, M Sakkal, R Beiram, S AbuRuz
A landscape review of nanomedicine platforms used in smart chemotherapy. Maps how surface chemistry, stimulus-responsive carriers, and combination approaches are being used to lower off-target toxicity.
Pharmaceuticals 17 (3), 315, 2024
M Sakkal, M Arafat, P Yuvaraju, R Beiram, S AbuRuz
First-author work on a theophylline controlled-release matrix system combining poloxamer 407, stearyl alcohol, and HPMC. Reports a formulation that survives multi-batch dissolution-profile testing.
Polymers 16 (5), 643, 2024
M Sakkal, M Arafat, P Yuvaraju, R Beiram, L Ali, M Altarawneh, ...
First-author follow-up on theophylline controlled-release tablets. Examines how hydration forms and polymer grades change release kinetics and how to control for them in formulation work.
Pharmaceuticals 17 (3), 271, 2024
M Arafat, M Sakkal, P Yuvaraju, A Esmaeil, V Poulose, S Aburuz
We show how excipient choice changes the immediate-release profile of generic metformin HCl tablets, with practical implications for formulation re-validation.
Pharmaceuticals 16 (4), 539, 2023
M Arafat, M Sakkal, MF Bostanudin, OA Alhanbali, P Yuvaraju, R Beiram, ...
Effect of enteric-coating film on the delayed release of pantoprazole gastro-resistant generic tablets. Walks through the formulation choices that survived re-validation across batches.
F1000Research 12, 1325, 2023
MM Hudaib, AF Abu Hajal, MM Sakkal
GC-MS characterisation of UAE-grown rosemary essential oil. Reports the major-constituent profile and contrasts it with regional sources.
Journal of Essential Oil Bearing Plants 25 (2), 282-289, 2022